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Relationship Between Serum Vitamins and Cognitive Impairment in the Elderly: A Study Based on the NHANES Database.
Brain Behav, 16(1):e71181, 01 Jan 2026
vitamins (vitamin B12, vitamin D, and FA) and their mixtures with cognitive impairment in the elderly, trying... serum vitamins (vitamin B12, vitamin D, and FA) and cognitive impairment in the elderly. Since the skewedCited by: 1 article | PMID: 41527474 | PMCID: PMC12796845
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Free full text in Europe PMCChinese expert consensus on dietary nutrition prescriptions and exercise intervention for sarcopenia (2025).
Asia Pac J Clin Nutr, 35(1):1-11, 01 Feb 2026
supplementing vitamin D at 800-1,000 IU/day for elderly individuals with insufficient vitamin D.29 N-3 polyunsaturated... mass and strength in the elderly.26 Vitamin D, by binding to its receptors, promotes calcium ion influxCited by: 0 articles | PMID: 41565227 | PMCID: PMC12823250
Review Free full text in Europe PMCSaveAdd to export listAssociation of 25-hydroxyvitamin D with sex hormones and body composition in Chinese older adults.
Front Endocrinol (Lausanne), 16:1714445, 17 Nov 2025
associated with vitamin D deficiency in the elderly population deserves attention. Vitamin D plays a pivotal... express vitamin D receptors, and various roles of vitamin D have thus been investigated (4–6). Vitamin D receptorsCited by: 0 articles | PMID: 41334436 | PMCID: PMC12665557
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Free full text in Europe PMCAssociations between vitamin D2 and metabolic indices in institutionalized older adults -a cross-sectional study.
J Physiol Pharmacol, 76(5):547-560, 01 Oct 2025
insufficient protein and vitamin D consumption. Serum 25(OH)D concentrations indicated vitamin D deficiency (17.6... are major contributors to vitamin D deficiency in older adults. While vitamin D3 is well studied, the metabolicCited by: 0 articles | PMID: 41364170
SaveAdd to export listVitamin D Supplementation in Orthopedic Trauma: Influence on Immune Modulation, Fracture Healing, and Infection Outcomes.
Cureus, 17(11):e97842, 26 Nov 2025
metabolite 1,25-dihydroxyvitamin D (1,25(OH)₂D), which binds to vitamin D receptors (VDRs) expressed in nearly... vulnerable population, presented with vitamin D deficiency [10]. Elderly patients demonstrate the highestCited by: 0 articles | PMID: 41312064 | PMCID: PMC12648633
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Free full text in Europe PMCVitamin D Deficiency Exacerbates d-Galactose-Induced Intestinal Barrier Dysfunction in a Murine Model of Intestinal Aging.
J Agric Food Chem, 73(39):24725-24740, 18 Sep 2025
intervention using a vitamin D3-withdraw diet (VDD) combined with d-galactose treatment was... Vitamin D deficiency is prevalent in the elderly population. The molecular mechanisms by which vitaminCited by: 0 articles | PMID: 40966548
SaveAdd to export listCirculating Muscle Markers for Sarcopenia in Peritoneal Dialysis.
Int J Nephrol, 2025:8817404, 15 Oct 2025
patients, however, remains unexplored. 3.2.3. Vitamin D Vitamin D is an essential nutrient and plays a crucial... that vitamin D is instrumental in promoting skeletal muscle regeneration by binding to vitamin D receptorsCited by: 0 articles | PMID: 41133236 | PMCID: PMC12543519
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Free full text in Europe PMCPositive association between the triglyceride-glucose index and lumbar bone mineral density in US postmenopausal women: A cross-sectional study from NHANES 2005 to 2018.
Medicine (Baltimore), 104(52):e46730, 01 Dec 2025
under a state of vitamin D deficiency, leading to increased levels of TG; moreover, vitamin D deficiency leads... index (BMI) n = 9; Smoking n = 1; 25-hydroxy vitamin D n = 55. Ultimately, a total of 1880 individualsCited by: 0 articles | PMID: 41465983 | PMCID: PMC12746976
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Free full text in Europe PMCOsteosarcopenia: epidemiology, molecular mechanisms, and management.
Front Endocrinol (Lausanne), 16:1577758, 28 Aug 2025
associated with impaired vitamin D synthesis and metabolism, often leading to vitamin D deficiency (64). This... chronic diseases associated with OS.4.3 Vitamin D Vitamin D is widely recognized as a critical regulatorCited by: 0 articles | PMID: 40951438 | PMCID: PMC12422917
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Free full text in Europe PMCAssociation between 25-hydroxy vitamin D levels and risk of frailty and pre-frailty in elderly adults: a systematic review and dose-response meta-analysis of epidemiologic studies with GRADE assessment.
J Transl Med, 23(1):1401, 17 Dec 2025
studies, especially in elderly subjects [43, 44]. Therefore, serum 25-hydroxy-vitamin D optimization could... relating to vitamin D (“Vitamin D” OR “cholecalciferol”) and frailty (frailty or “frail elderly”). All systematicCited by: 0 articles | PMID: 41408560 | PMCID: PMC12709776
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Free full text in Europe PMCEffects of Resistance Training Combined with Vitamin D Supplementation on Health-Related Variables in the Elderly: Muscle Strength, Body Composition, and Inflammatory Status.
Int J Environ Res Public Health, 22(11):1695, 10 Nov 2025
health of the elderly. This condition can be mitigated by resistance training (RT) and vitamin D supplementation... tissue and the number of active vitamin D receptors, given that vitamin D plays an important role in adipocyteCited by: 0 articles | PMID: 41302641 | PMCID: PMC12652358
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Free full text in Europe PMCA Prospective Observational Study Investigating the Relationship Between Vitamin D Deficiency and STOP-Bang Parameters in Elderly Populations.
Nat Sci Sleep, 17:2399-2410, 29 Sep 2025
and vitamin D deficiency in an elderly Asian population. A potential relationship between vitamin D levels... indicators of vitamin D deficiency, particularly in elderly Asian populations. Given that vitamin D deficiencyCited by: 0 articles | PMID: 41050641 | PMCID: PMC12493112
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Free full text in Europe PMCMuscle function mediates the association between vitamin D deficiency and hip fracture risk: a retrospective study in older adults.
Front Endocrinol (Lausanne), 16:1658529, 05 Nov 2025
skin to synthesize vitamin D decreases, as does the number of vitamin D receptors in human tissues (5... bone metabolism, vitamin D is critically important for skeletal muscle. Vitamin D receptors (VDRs) are expressedCited by: 0 articles | PMID: 41268162 | PMCID: PMC12626798
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Free full text in Europe PMCVitamin D and cancer-related fatigue in elderly patients: mechanisms and therapeutic insights-a narrative review.
Front Nutr, 12:1642166, 29 Sep 2025
the challenge of elderly cancer-related fatigue (CRF) and a new perspective on vitamin D (VD) intervention... of VD in alleviating elderly CRF.Illustration depicting the effects of Vitamin D on various health factorsCited by: 0 articles | PMID: 41089276 | PMCID: PMC12515685
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Free full text in Europe PMCSarcopenia in the Aging Process: Pathophysiological Mechanisms, Clinical Implications, and Emerging Therapeutic Approaches.
Int J Mol Sci, 26(24):12147, 17 Dec 2025
Furthermore, vitamin D supplementation has been found to improve muscle strength, particularly in elderly individuals... individuals with low serum vitamin D levels [248,250]. Studies have shown that vitamin D is essential for skeletalCited by: 0 articles | PMID: 41465572 | PMCID: PMC12734266
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Free full text in Europe PMCBaduanjin Exercise, With or Without Vitamin D, Outperforms Vitamin D Alone in Reducing Frailty Among Institutionalized Older Adults: A Cluster-Based Randomized Controlled Trial.
Nutrients, 17(23):3795, 03 Dec 2025
transcription factor expression, possibly because vitamin D receptors are predominantly present in proliferating... and intervention for elderly patients with frailty [24]. At baseline, serum vitamin D levels were measuredCited by: 0 articles | PMID: 41374085 | PMCID: PMC12694498
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Free full text in Europe PMCVitamin D alleviates obesity-related metabolic abnormalities by modulating the gut microbiota in older female mice on a high-fat diet.
Front Cell Infect Microbiol, 15:1703497, 10 Dec 2025
that vitamin D ameliorates obesity and metabolic abnormalities in high-fat diet-induced elderly female... metabolism abnormalities through vitamin D supplementation in elderly women. The accumulation of lipidsCited by: 0 articles | PMID: 41450574 | PMCID: PMC12727612
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Free full text in Europe PMCModulation of Cardiometabolic Risk by Vitamin D and K2: Simple Supplementation or Real Drug? Uncovering the Pharmacological Properties.
Int J Mol Sci, 27(1):298, 27 Dec 2025
diabetes. Vitamin D receptors are expressed in pancreatic β-cells, and evidence suggests that vitamin D enhances... the VDR (Vitamin D Receptor), which is part of a larger family of transcription factor receptors. When 1,25Cited by: 0 articles | PMID: 41516172 | PMCID: PMC12785717
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Free full text in Europe PMCHigher dietary vitamin D intake influences brain and mental function in elderly Americans: a cross-sectional analysis.
Front Nutr, 12:1564568, 09 Apr 2025
molecular mechanisms. Vitamin D activates receptors in the brain, such as vitamin D receptors (VDRs) (7), which... dietary vitamin D intake from 2007–2008 to 2017–2018 among the elderly population, dietary vitamin D intakeCited by: 1 article | PMID: 40271436 | PMCID: PMC12016215
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Free full text in Europe PMCUnraveling the Causal Linkages of RBP7 and SCGB3A1 on Pelvic Organ Prolapse: Multifaceted Insights From Genome-Wide Mendelian Randomization, Single-Cell RNA Analysis, and Network Pharmacology.
Biomed Res Int, 2026:9785848, 04 Jan 2026
Moreover, vitamin A also has an indirect impact on collagen fibers by influencing ECM receptors and related... ECM receptors like integrins can interact with collagen fibers [51, 52]. A deficiency of vitamin A mayCited by: 0 articles | PMID: 41497737 | PMCID: PMC12765987
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Free full text in Europe PMCBibliometric and Visualized Analysis of the Global Research Status and Trends of the Association Between Vitamin D and Osteoarthritis in the Last Two Decades.
J Multidiscip Healthc, 18:7779-7795, 01 Dec 2025
hormone with diverse biological functions. Vitamin D receptors are expressed in numerous tissues including... prevalence in elderly populations—the demographic most affected by OA.9 All these suggest that vitamin D may modulateCited by: 0 articles | PMID: 41358012 | PMCID: PMC12680506
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Free full text in Europe PMCThe protective role of appendicular lean mass in osteoporosis development among postmenopausal type 2 diabetes patients.
Sci Rep, 15(1):40819, 19 Nov 2025
decline in renal synthesis of 1,25-(OH)₂D contributes to vitamin D deficiency, further promoting bone loss... association between serum 25(OH)D levels and osteoporosis risk, whereby higher vitamin D levels did not appearCited by: 0 articles | PMID: 41258171 | PMCID: PMC12630904
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Free full text in Europe PMCAssociation Between Vitamin A and D Status and the Risk of COVID-19 in the Elderly Population: A Single-Center Experience.
J Inflamm Res, 18:8233-8241, 24 Jun 2025
years), elderly COVID-19 patients in our analysis demonstrated significantly lower vitamin D levels and... prevalence of vitamin D deficiency.45–48 Notably, even control subjects in this elderly population exhibitedCited by: 0 articles | PMID: 40585048 | PMCID: PMC12205746
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Free full text in Europe PMCNeuroprotective synergy of vitamin D and exercise: a narrative review of preclinical and clinical evidence on aging-related neuroplasticity and cognitive health.
Front Nutr, 12:1642363, 09 Sep 2025
older adults (8–10). Vitamin D, acting through widely distributed vitamin D receptors (VDRs) and local activation... dihydroxyvitamin D₃, crosses the blood–brain barrier and binds to vitamin D receptors (VDRs) widely expressedCited by: 0 articles | PMID: 40995182 | PMCID: PMC12454393
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Free full text in Europe PMCDiet for the prevention and treatment of Parkinson's disease.
Front Nutr, 12:1587246, 17 Dec 2025
the disease.3 Vitamins3.1 Vitamin D Vitamin D (VD) is a fat-soluble vitamin consisting mainly of VD2 (... illustrating vitamin D and vitamin C pathways in neural health. Panel A shows sources of vitamin D and itsCited by: 0 articles | PMID: 41479664 | PMCID: PMC12753417
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