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Sequential BCR::ABL1 evaluation during dose de-escalation in peripheral blood is more predictive of TFR success than single assessment at dose de-escalation in either peripheral blood or bone marrow.

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Affiliations

  • 1. Paul O'Gorman Leukaemia Research Centre, School of Cancer Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, UK.
      Authors
    • Patterson SD 1
    • Hair A 1
    • Jørgensen HG 1
    • Wheadon HW 1
    • Copland M 1
    (5 authors)
  • 2. Institute for Medical Informatics and Biometry, Faculty of Medicine, Technische Universität Dresden, Dresden, Germany.
      Authors
    • Gottschalk A 2
    • Glauche I 2
    • Roeder I 2
    (3 authors)
  • 3. SIHMDS, North West London Pathology, London, UK.
      Authors
    • Hayden C 3
    (1 author)
  • 4. Robertson Centre for Biostatistics, School of Health and Wellbeing, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, UK.
      Authors
    • Young R 4
    (1 author)
  • 5. Centre for Haematology, Imperial College London, London, UK.
      Authors
    • Apperley JF 5
    (1 author)
    • Show all (6)

ORCIDs linked to this article

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Leukemia, 07 Jan 2026,
https://doi.org/10.1038/s41375-025-02853-7 PMID: 41501502 

Abstract 

No abstract provided.

Full text links 

Read article at publisher's site: https://doi.org/10.1038/s41375-025-02853-7

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    Funding 

    Funders who supported this work.

    Blood Cancer UK (2)

    Cancer Research UK (1)

    • Grant ID: CRCPJT/100006

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