Europe PMC

This website requires cookies, and the limited processing of your personal data in order to function. By using the site you are agreeing to this as outlined in our privacy notice and cookie policy.

Abstract 


Depression is a common comorbidity in dementia, with prevalence ranging from 20 to 60% across different countries. This study examined whether depressive symptom severity levels differ by dementia characteristics and country of residence in people living with dementia. This cross-sectional analysis used baseline data from 376 participants in the HOMESIDE trial. Linear regression models examined differences in depressive symptom severity levels by dementia stage, type, severity, and country. In this sample (57% male, mean age 76.6 years), depressive symptom scores were higher for people with severe cognitive impairment than those with mild dementia (MMSE 24-30) (adjusted mean difference: 3.78, 95% CI 1.60-5.96). Mean depressive symptom severity was lower in Norway, Germany, and United Kingdom compared to Australia, with no significant difference for Poland. No apparent differences by dementia type or stage were found. Depressive symptom severity levels differed by cognitive impairment severity and country. Cross-national differences likely reflect a complex interplay of healthcare systems, cultural factors, family support structures, and societal approaches to dementia care. Regular depressive symptom screening is recommended, particularly for severe dementia.Trial registration: ACTRN12618001799246 (Australian New Zealand Clinical Trials Registry) and NCT03907748 (ClinicalTrials.gov).

Free full text 


loading

Citations & impact 


This article has not been cited yet.

loading

Data 


loading

Similar Articles 


To arrive at the top five similar articles we use a word-weighted algorithm to compare words from the Title and Abstract of each citation.


    Funding 


    Funders who supported this work.

    Alzheimer's Society (2)

    • Grant ID: grant no. 462

    • Grant ID: 462

    Alzheimer’s Society, UK (1)

    • Grant ID: grant no. 462

    Federal Ministry of Education and Research Germany (1)

    • Grant ID: 01ED1901

    National Health and Medical Research Council, Australia (1)

    • Grant ID: GNT1169867

    Norwegian Research Council (1)

    • Grant ID: Project number 298995

    The National Centre for Research and Development, Poland (1)

    • Grant ID: JPND/04/2019

    • Save

    • Open PDF

    • Claim to ORCID